Vascular Rehabilitation Benefits of Tribulus Terrestris (TT), Taurine and High Dose Alpha Lipoic Acid (ALA) Supplementation with Interval Walking Training Program after Surgical Vascular Bypass Treatment (Pilot Study)

Sid Solakovic Solakovic, Ratko Pavlovic, Mensur Vrcic, Emir Solakovic

Abstract


Background: Some of main raisons for the elderly graft occlusion after successful aortal-iliac, aortal Femoral and Femoral Distal Vein Bypass, progression of main disease, continuing bad life Habits and uncontrolled risk factors such are mostly: poor nutrition traditional or fast food, Smocking and Lacks of Walking and Physical Activity Habits. Objective: The primary objective of the study was to estimate influence of Interval Walking Training Program combine with Tribulus Terrestris, 3-5 gram of Taurine and high dose of 1800mg supplementation of ALA on primary potency and vascular treatment. Secondary goals of this study is determinate by establishing better understanding connection between ordinary vascular walking therapy 30-45 min and interval walking program combine with Tribulus Terrestris, Taurine and high dose of and ALA as secondary supplementation after surgical and endovascular treatment. Methodology: The study included 112 patients, at the Clinic of cardiovascular surgery, Clinical Center University of Sarajevo, age between 50 and 75 (50 patients surgical treated with aortic-iliac, aortic-femoral and femoral distal vein bypass with and without Linton-patch/Taylor patch-first group) and (62 endovascular Iliac treated patients (indication TASC II A and B) with and without support Tribulus Terrestris, high dose of ALA and Taurine - second group). Results: Final analysis has reveal the rehabilitation outcome in 83% patients with bypass above the knee was fully rehabilitated compared to 46,6% patients with bypass below the knee was statistically considered significant by using p value less than (p<0,05) In anamnestic history in 83% patient with amputation above the knee was documented the presence of hypertension, hyperlipidemia, nicotinismus and diabetes compared to 66,7% of patients with amputation level below the knee but there was no statistically significant difference (p>0,05). Conclusion: Interval Walking Training Program on Tribulus Terrestris, Taurine and high dose of ALA had a significantly and successfully higher bypass potency and rehabilitation prognosis compare to patients without supplementation and postsurgical physical therapy concept. It is obviously the is certain link between physical activity, life style modification and serum testosterone on primary bypass potency.

Keywords


Vascular Artery Bypass, Inteval Training, Tribulus Terrestris, Taurine, Vascular Diseases

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References


Abbott WM, Green RM, Matsumoto T, Wheeler JR, Miller N, Veith FJ, et al. (1997). Prosthetic above-knee femoropopliteal bypass grafting: results of a multicenter randomized prospective trial. Above-Knee Femoropopliteal Study Group. Journal of Vascular Surgery, 25,19–28.

Abu Rahma AF, Robinson PA, Holt SM. (1999). Prospective controlled study of Dacron versus saphenous vein in claudicant patients with bilateral above knee femoropopliteal bypasses. Surgery, 126 (4), 594–601.

Aronow WS, & Ahn C. (2004). Prevalence of coexistence of coronary artery disease,periferal arterial disease and atherothrombotic brain infraction in men and woman older than 62 years. American Journal of Cardiology, 74 (1), 64-65. DOI:10.1016/0002-9149(94)90493-6

Arany E, Strutt B, Romanus P, Remacle C, Reusens B, Hill DJ.(2004). Taurine supplement in early life altered islet morphology, decreased insulitis and delayed the onset of diabetes in non-obese diabetic mice. Diabetologia, 47(10),1831-1837. DOI:10.1007/s00125-004-1535-z

Abirami P, Rajendran A. (2011). GC-MS analysis of Tribulus terrestris. Asian Journal Plant Science and Research, 1(4),13–16.

Brøns C, Spohr C, Storgaard H, Dyerberg J, Vaag A. (2004). Effect of taurine treatment on insulin secretion and action, and on serum lipid levels in overweight men with a genetic predisposition for type II diabetes mellitus. European Journal of Clinical Nutrition, (9),1239-1247. DOI:10.1038/sj.ejcn.1601955

Braunstein GD, Sundwall DA, Katz M, Shifren JL, Buster JE, Simon JA, Bachman G, Aguirre OA, Lucas JD, Rodenberg C, Buch A, Watts NB. (2005). Safety and efficacy of a testosterone patch for the treatment of hypoactive sexual desire disorder in surgically menopausal women: a randomized, placebo-controlled trial. Archives of Internal Medicine.25,165(14),1582-1589. DOI:10.1001/archinte.165.14.1582

Berkman Z, Tanriover G, Acar G, Sati L, Altug T, Demir R. (2009). Changes in the brain cortex of rabbits on a cholesterol-rich diet following supplementation with a herbal extract of Tribulus terrestris. Histology and Histopathology. 24(6),683-692. doi: 10.14670/HH-24.683

Carrasco, L. (2017). The Effect of Sprint Training for Reducing Body Fat in Women. Strength and Conditioning Journal. 39 (4), 89 – 96. doi: 10.1519/SSC.0000000000000300

Dormandy, JA., Mahir, M, Ascady G et al. (1989). Fate of patient with chronic leg ishemia. A review article. Journal of Cardiovascular Surgery. 30(1), 50-57.

Dennerstein L, Koochaki P, Barton I, Graziottin A. (2006). Hypoactive sexual desire disorder in menopausal women: a survey of western European women. The Journal of Sexual Medicine. 3 (2),212–222. DOI:10.1111/j.1743-6109.2006.00215.x

Evans LE, Webster MW, Brooks DH, Bahnson HT.(1981). Expanded polytetrafluoroethylene femoropopliteal grafts: forty-eight-month follow-up. Surgery. 89,16–22.

Esfandiari A, Dehghan A, Sharifi S, Vesali E (2011). Effect of Tribulus Terresteris extract on ovarian activity in immature wistar rat: a histological evaluation. Journal of Animal Veterinary Advances. 7(10),883–886. DOI: 10.3923/javaa.2011.883.886

Herzberg GR et al. (2004). Aerobic exercise, lipoproteins, and cardiovascular disease: benefits and possible risks.ed Canadian Journal of Applied Physiology. 29(6),800-807.

Harding SV, Rideout TC, Jones PJ et al. (2012). Evidence for using alpha-lipoic acid in reducing lipoprotein and inflammatory related atherosclerotic risk. Journal of Diet Supplement. 9(2),116-127. DOI:10.3109/19390211.2012.683136

Hooper DR., Kraemer WJ, Saenz C, Schill KE, Focht BC, Volek JS, Maresh CM .(2017). The presence of symptoms of testosterone deficiency in the exercise-hypogonaedal male condition and the role of nutrition. European Journal of Applied Physiology. 117(7),1349-1357. doi: 10.1007/s00421-017-3623-z.

Ito T, Schaffer SW, Azuma J. (2012). The potential usefulness of taurine on diabetes mellitus and its complications. Amino Acids.42(5),1529-1539. doi: 10.1007/s00726-011-0883-5.

Ivanova S, Ivanov K, Mladenov R, Papanov S, Ivanova S, Obreshkova D, Atanasov PPV. (2016). Food supplements with anabolic and androgenic activity UHPLC analysis of food additives, containing Tribulus terrestris extract. World Journal of Pharmaceutical Research.5 (3), 6–13.

Johnson WC, Lee KK. (2000). A comparative evaluation of polytetrafluoroethylene, umbilical vein, and saphenous vein bypass grafts for femoral-popliteal above-knee revascularization: a prospective randomized Department of Veterans Affairs cooperative study. Journal of Vascular Surgery.32,268–277.

Kueger C et al. (2002). Peripheral arterial Diseae:Aging and Comorbidity,In Lanzer P,Topol EJ:hrsg. Pan Vascular medicin Berlin,Hedelberg, New York: Springer;1449-1470.

Keating, S.E., Johnson, N.A., Mielke, G.I., & Coombes, J.S. (2017). A systematic review and meta-analysis of interval training versus moderate-intensity continuous training on body adiposity. Obesity of Review. 18(8), 943-964. doi: 10.1111/obr.12536.

Leiblum SR, Koochaki PE, Rodenberg CA, Barton IP, Rosen RC. (2006). Hypoactive Sexual desire disorder in postmenopausal women: US results from the Women’s International Study of Health and Sexuality (WISHeS). Menopause. 13(1),46–56. DOI:10.1097/01.gme.0000172596.76272.06

Li M, Guan Y, Liu J, Zhai F, Zhang X, Guan L. (2013). Cellular and molecular mechanisms in vascular smooth muscle cells by which total saponin extracted from Tribulus terrestris protects against artherosclerosis. Cell Physiology and Biochemistry, 32(5),1299-1308. doi: 10.1159/000354528.

Olas B, Hamed AI, Oleszek W, Stochmal A, et al. (2015). Extracts from Tribulus species may modulate platelet adhesion by interfering with arachidonic acid metabolism. Platelets.26(1), 87-92. doi: 10.3109/09537104.2013.867426

Prendiville EJ, Yeager A, O’Donnell TF, Coleman JC, Jaworek A, Callow AD, et al.(1990). Long-term results with the above-knee popliteal expanded polytetrafluoroethylene graft. Journal of Vascular Surgery.11,517–524.

Poletti LF, Matsuura JH, Dattilo JB, Posner MP, Lee HM, Scouvart M, et al. (1998). Should vein be saved for future operations? A 15-year review of infrainguinal bypasses and the subsequent need for autogenous vein. Annals of Vascular Surgery.12,143–147. DOI:10.1007/s100169900131

dealing with lower extremity ischemia: revised version. Journal of Vascular Surgery. 26,517–538.

Rutherford JA, Spriet LL, Stellingwerff T. (2010). The effect of acute taurine ingestion on endurance performance and metabolism in well-trained cyclists. International Journal of Sport Nutrition and Exercise Metabolism. 20(4), 322-329

Rogerson S, Riches CJ, Jennings C, Weatherby RP, Meir RA, Marshall Gradisnik SM.(2007). The effect of five weeks of Tribulus terrestris supplementation on muscle strength and body composition during preseason training in elite rugby league players. Journal of Strength Conditioning Research. 21 (2), 348–53. DOI:10.1519/R-18395.1

Sayers RD, Raptis S, Berce M, Miller JH.(1998). Long-term results of femorotibial bypass with vein or polytetrafluoroethylene. British Journal of Surgery.85 (7),934–938. DOI:10.1046/j.1365-2168.1998.00765.x

Sharifi AM, Darabi R, Akbarloo N. (2003). Study of antihypertensive mechanism of Tribulus terrestris in 2K1C hypertensive rats: role of tissue ACE activity. Life Science.73(23),2963-2971. DOI:10.1016/j.lfs.2003.04.002

Svartberg, J., von Muhlen, D., Mathiesen, E. et al. (2006). Low testosterone levels are associated with carotid atherosclerosis in men. Journal of Internal Medicine. 259, 576–582. DOI:10.1111/j.1365-2796.2006.01637.x

Silva LA, Silveira PC, Ronsani MM, Souza PS, Scheffer D, Vieira LC, Benetti M, De Souza CT, Pinho RA. (2011). Taurine supplementation decreases oxidative stress in skeletal muscle after eccentric exercise. Cell Biochemistry Function. 29(1),43-49. doi: 10.1002/cbf.1716.

Solaković, S., Vrcić, M., & Pavlović, R. (2016). Benefits of physical activity on diabetic andnon-diabetic patients in fontaine's stage Iia of peripheral artery disease in Bosnia and Herzegovina. Journal of Physical Education Research, 3 (2), 23-33.

Simon-Higgins, A., Michael V. Fedewa,AB., Elizabeth D. Hathaway,A., et al. (2016). Sprint interval and moderate-intensity cycling training differentially affect adiposity and aerobic capacity in overweight young-adult women. Applied Physiology, Nutrition, and Metabolism 41(11),1177-1118. DOI:10.1139/apnm-2016-0240

Tuncer MA, Yaymaci B, Sati L, Cayli S, Acar G, Altug T, Demir R. (2009). Influence of Tribulus terrestris extract on lipid profile and endothelial structure in developing atherosclerotic lesions in the aorta of rabbits on a high-cholesterol diet. Acta Histochemica.111(6), 488-500. doi: 10.1016/j.acthis.2008.06.004

Türk, Y., Theel, W., Kasteleyn, M.J., Franssen, F.M.E., Hiemstra, P.S., Rudolphus, A., Taube, C. & Braunstahl, G.J. (2017). High intensity training in obesity: a Meta-analysis. Obesity Science & Practice. 3(3), 258-271. doi: 10.1002/osp4.109.

Zhu W, Du Y, Meng H, Dong Y, Li L. (2017). A review of traditional pharmacological uses, phytochemistry, and pharmacological activities of Tribulus terrestris. Chemistry Central Journal. 11(1),60. doi: 10.1186/s13065-017-0289-x.

Yang J, Wu G, Feng Y, Lv Q, Lin S, Hu J. (2010). Effects of taurine on male reproduction in rats of different ages. Journal of Biomedical Scences. 17 Suppl 1:S9. doi: 10.1186/1423-0127-17-S1-S9




DOI: https://doi.org/10.7575/aiac.ijkss.v.7n.3p.22

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